General Playback Options - Error in Saving Settings

Yesterday I was experiencing frequent dropouts listening to Spotify. So I started looking for ways to reduce the load on the system. Checked off HDMI output, Checked off upsampling, and maybe a few others. I lost audio on the system and when I restart it gives the red error on upper right, “General Playback Options - Error in Saving Settings”. After another restart the audio (SPDIF) is up now but I think the error may still be lingering. Any idea what may cause this? Thanks!

I have the same message.
I swiched to audio out and got sound on my Schiit Mjolnir. Switched back and everything seems to work but no sound. The I began seeing this message.

NO Response ti mieuba, has no one else seen this error?